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Mechanism of action Tadalafil is an effective, reversible, selective inhibitor of specific phosphodiesterase type 5 (PDE-5), cyclic guanosine monophosphate (cGMP). When sexual stimulation causes local release of nitric oxide, inhibition of PDE-5 tadalafilom leads to increased levels of cGMP in the cavernous body of penis. more...

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about 8 years ago

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