Open Atrium is a team portal starter package build as a Drupal profile. What makes it unique is that it's extensible and customizable. This means that you - and everyone - can develop new features for it, add other modules, change the skin, totally re-factor the workflow, and do anything else that you can think up to make Open Atrium meet your exact needs.
Open Atrium is being translated in more than twenty languages and several hundred people are growing its base of features
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