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The package was written to explore the electrical wave propagation in a minimally realistic fiber architecture model of the left ventricle (LV). Experimental results (C. Eyster, 1957) indicate a nested, layered geometry for the fiber surfaces of the left ventricle, where fiber directions are approximately aligned in each surface and gradually rotate throughout the thickness of the ventricle. Numerical and analytical results have highlighted the importance of this rotating anisotropy and its possible destabilizing role on the dynamics of scroll waves in excitable media with application to the heart. Motivated by a first principles derivation by Peskin (Peskin, 1989) of the anisotropic diffusion tensor of the LV wall, we implemented a minimally realistic model of the left ventricle that adequately captures the geometry and anisotropic properties of the heart as a conducting medium while being easily parallelizable and computationally more tractable than fully realistic anatomical models. Studies using such a minimal model are complementary to fully realistic and anatomically-based computational approaches, allowing the addition of successively realistic features, thereby providing unique insight into the basic mechanisms of formation and obliteration of electrical wave instabilities.

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fiber heart scientific simulation

In a Nutshell, 3d-heart-simulation...

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