Yubico's Windows-based Personalization tool allows you to re-initialize the AES key in your Yubikey. The purpose is that only you will know the AES key of your Yubikey. Yubico is not aware of it so Yubico can't validate the OTP generated from it. To validate OTPs generated from your newly programmed Yubikey you need to host your own Yubikey validation server and put the same AES key in the server's database so you can validate the OTP from your Yubikey.
A convenience bonus feature is that you can also configure your Yubikey to set a long static password.
The download comes with documentation and examples. We currently do not support Mac OS X or GNU/Linux but are open to help from the community to port the package.
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These details are provided for information only. No information here is legal advice and should not be used as such.