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Description Estimates toxic hazard of chemical compounds. The latest version includes the following toxicity prediction modules: -Cramer rules (oral toxicity) -Toxicity mode of action via Verhaar scheme -Skin irritation prediction -Eye irritation prediction -Benigni / Bossa rulebase for ... [More] mutagenicity and carcinogenicity prediction -START biodegradation and persistence prediction -Structure Alerts for identification of Michael Acceptors -Structure Alerts for skin sensitisation -Kroes TTC Decision tree -SMARTCyp - Cytochrome P450-Mediated Drug Metabolism and metabolites prediction -Structure Alerts for the in vivo micronucleus assay in rodents (ISSMIC) -Structural Alerts for Functional Group Identification (ISSFUNC) Pplugin framework to incorporate different approaches. [Less]

(Q)SAR Model Reporting Format (QMRF) is a template format developed at the Computational Toxicology and Modelling lab of the JRC's Institute for Health and Consumer Protection. It is intended for summarising and reporting key information on (Q)SAR models, including the results of any validation ... [More] studies. The information is structured according to the OECD (Q)SAR validation principles. The JRC's QSAR Model Database is freely accessible with the help of the following applications: * QMRF Editor: a Java application, which provides user friendly interface for editing QMRF files. * QMRF Inventory: a web application, allowing users to submit, publish, and search QMRF files. [Less]